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Target
Glutamate receptor ionotropic, kainate 3
Ligand
BDBM50004897
Substrate
n/a
Meas. Tech.
ChEBML_88659
Ki
>100000±n/a nM
Citation
 Whitten, JP; Baron, BM; Muench, D; Miller, F; White, HS; McDonald, IA (R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex. J Med Chem 33:2961-3 (1990) [PubMed]  Article 
Target
Name:
Glutamate receptor ionotropic, kainate 3
Synonyms:
GRIK3_RAT | Glur7 | Glutamate receptor ionotropic kainate 3 | Glutamate receptor ionotropic, kainate | Grik3
Type:
PROTEIN
Mol. Mass.:
104080.46
Organism:
Rattus norvegicus
Description:
ChEMBL_1447329
Residue:
919
Sequence:
MTAPWRRLRSLVWEYWAGFLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQSLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNAHVSAIVEKWSMERLQAAPRAESGLLDGVMMTDAALLYDAVHIVSVCYQRASQMTVNSLQCHRHKPWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFIYKLRKTAEREQRSFCSTVADEIRFSLTCQRRLKHKPQPPMMVKTDAVINMHTFNDRRLPGKDSMSCSTSLAPVFP
  
Inhibitor
Name:
BDBM50004897
Synonyms:
(APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Amino-5-phosphono-pentanoic acid | (R)-2-amino-5-phosphonopentanoicacid | 2-Amino-5-phosphono-pentanoic acid | 2-Amino-5-phosphono-pentanoic acid anion | 2-Amino-5-phosphono-pentanoic acid(D-AP5) | 2-Amino-5-phosphono-pentanoic acid(R-AP5) | 2-Amino-5-phosphono-pentanoic acid(S-AP5) | CHEMBL28862 | DL-2-amino-5-phosphono valericacid | DL-2-amino-5-phosphonovaleric acid
Type:
Small organic molecule
Emp. Form.:
C5H12NO5P
Mol. Mass.:
197.1262
SMILES:
NC(CCCP(O)(O)=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: