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Found 932 with Last Name = 'whitten' and Initial = 'jp'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054245(5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054252(5-Bromo-N-cyclopropylmethyl-2-methyl-N-propyl-N'-(...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054250(CHEMBL306482 | N-Cyclopropylmethyl-2,5-dimethyl-N-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054248(2,5-Dimethyl-N,N-dipropyl-N'-(2,4,6-trichloro-phen...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054253(CHEMBL77716 | N-Cyclopropylmethyl-5-ethyl-2-methyl...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataKi:  5nMAssay Description:Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204(CHEMBL63989 | [4-(2-Chloro-4,6-dimethoxy-phenyl)-p...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(CHEMBL65484 | Dicyclopropylmethyl-propyl-[4-(2,4,6...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144191(CHEMBL61954 | Dicyclopropylmethyl-[4-(2,4-dimethox...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144194(CHEMBL293627 | Dicyclopropylmethyl-[4-(2,4-dimetho...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054246(CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...)
Affinity DataKi:  30nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144196(CHEMBL63029 | [4-(4-Bromo-phenyl)-5-methyl-pyrimid...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054225(CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Affinity DataKi:  57nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054225(CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Affinity DataKi:  57nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144197(CHEMBL66249 | [4-(4-Bromo-2-methyl-phenyl)-5-methy...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144200(CHEMBL63457 | Dicyclopropylmethyl-[4-(2-fluoro-4,6...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054249(CHEMBL140175 | N*4*-Cyclopropylmethyl-6-methyl-N*4...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144203(Allyl-dicyclopropylmethyl-[4-(2,4,6-trimethoxy-phe...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054226(CHEMBL77391 | N,N-Diallyl-6-methyl-N'-(2,4,6-trime...)
Affinity DataKi:  115nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054230(6-Methyl-N,N-dipropyl-N'-(2,4,6-trimethyl-phenyl)-...)
Affinity DataKi:  130nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054247(CHEMBL344805 | N-Cyclopropylmethyl-2,5,N'-trimethy...)
Affinity DataKi:  150nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144202(((R)-Cyclopropyl-phenyl-methyl)-propyl-[4-(2,4,6-t...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144192(CHEMBL291657 | [4-(4-Bromo-phenyl)-5,6-dimethyl-py...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144190(CHEMBL302396 | Propyl-(1-thiophen-2-yl-cyclopropyl...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054244(CHEMBL134475 | N-Cyclopropylmethyl-2-methyl-N-prop...)
Affinity DataKi:  253nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144201(CHEMBL305354 | Dicyclopropylmethyl-[4-(2,4-dimetho...)
Affinity DataKi:  460nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054221(CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...)
Affinity DataKi:  490nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054216(CHEMBL307419 | N-Benzyl-6-methyl-N-propyl-N'-(2,4,...)
Affinity DataKi:  490nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144199((1-Furan-3-yl-cyclopropyl)-propyl-[4-(2,4,6-trimet...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144195(CHEMBL63585 | Dicyclopropylmethyl-[4-(2,4-dimethox...)
Affinity DataKi:  860nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054239(CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054219(CHEMBL305671 | N-Benzyl-N-butyl-6-methyl-N'-(2,4,6...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054255(CHEMBL80806 | N-Cyclopropylmethyl-2-methyl-N-propy...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054223(CHEMBL307871 | N-Benzyl-N-ethyl-6-methyl-N'-(2,4,6...)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054241(6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...)
Affinity DataKi:  1.69E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054238(CHEMBL137434 | N-Benzyl-N'-(2,6-diethyl-phenyl)-N-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144198(CHEMBL305583 | Propyl-(1-thiophen-3-yl-cyclopropyl...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054234(6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144189(CHEMBL65979 | Cyclopentyl-propyl-[4-(2,4,6-trimeth...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054222(CHEMBL136519 | N,N-Diallyl-N'-(2,6-diethyl-phenyl)...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054229(CHEMBL136828 | N-Cyclopropylmethyl-N'-(2,4-dimetho...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054254(CHEMBL136593 | N-Cyclopropylmethyl-N-propyl-N'-(2,...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054236(6-Methyl-N-p-tolyl-N'-(4-trifluoromethyl-benzyl)-[...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054224(CHEMBL138124 | N,N-Diallyl-6-methyl-N'-p-tolyl-[1,...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054231(CHEMBL137291 | N-Benzyl-N'-(2,6-diethyl-phenyl)-6-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054227(CHEMBL136596 | N-Benzyl-N'-(2,6-dimethyl-phenyl)-6...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054243(CHEMBL343958 | N-Benzyl-N-ethyl-6-methyl-N'-p-toly...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054233(CHEMBL343704 | N-Cyclopropylmethyl-N'-(2,6-diethyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054220(CHEMBL135615 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054251(CHEMBL138687 | N*2*-Cyclopropylmethyl-6-methyl-N*2...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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