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Target
Somatostatin receptor type 3
Ligand
BDBM50370059
Substrate
n/a
Meas. Tech.
ChEMBL_200699 (CHEMBL872701)
Ki
450±n/a nM
Citation
 Rajeswaran, WG; Hocart, SJ; Murphy, WA; Taylor, JE; Coy, DH Highly potent and subtype selective ligands derived by N-methyl scan of a somatostatin antagonist. J Med Chem 44:1305-11 (2001) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50370059
Synonyms:
CHEMBL1794041
Type:
Small organic molecule
Emp. Form.:
C58H69ClN12O9S2
Mol. Mass.:
1177.826
SMILES:
C[C@H](O)[C@H]1NC(=O)C(CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(Cc2cccnc2)N(C)C(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)NC(Cc1ccc2ccccc2c1)C(N)=O)NC(=O)C(N)Cc1ccc(Cl)cc1
Structure:
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