Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50151719
Substrate
n/a
Meas. Tech.
ChEMBL_302767 (CHEMBL876356)
Ki
5.9±n/a nM
Citation
 Alikhani, V; Beer, D; Bentley, D; Bruce, I; Cuenoud, BM; Fairhurst, RA; Gedeck, P; Haberthuer, S; Hayden, C; Janus, D; Jordan, L; Lewis, C; Smithies, K; Wissler, E Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity. Bioorg Med Chem Lett 14:4705-10 (2004) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50151719
Synonyms:
CHEMBL363329 | N-[2-Hydroxy-5-(1-hydroxy-2-{2-[4-(3-phenyl-propoxy)-phenyl]-ethylamino}-ethyl)-phenyl]-formamide
Type:
Small organic molecule
Emp. Form.:
C26H30N2O4
Mol. Mass.:
434.5274
SMILES:
O[C@@H](CNCCc1ccc(OCCCc2ccccc2)cc1)c1ccc(O)c(NC=O)c1
Structure:
Search PDB for entries with ligand similarity: