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Target
Cholecystokinin receptor type A
Ligand
BDBM50418885
Substrate
n/a
Meas. Tech.
ChEMBL_757822 (CHEMBL1809766)
Ki
17378.01±n/a nM
Citation
 Roberts, K; Ursini, A; Barnaby, R; Cassarà, PG; Corsi, M; Curotto, G; Donati, D; Feriani, A; Finizia, G; Marchioro, C; Niccolai, D; Oliosi, B; Polinelli, S; Ratti, E; Reggiani, A; Tedesco, G; Tranquillini, ME; Trist, DG; van Amsterdam, FT Synthesis and structure-activity relationship of new 1,5-dialkyl-1,5-benzodiazepines as cholecystokinin-2 receptor antagonists. Bioorg Med Chem 19:4257-73 (2011) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50418885
Synonyms:
CHEMBL1808412
Type:
Small organic molecule
Emp. Form.:
C26H35N5O4
Mol. Mass.:
481.5872
SMILES:
COc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN(C)C)C2=O)cc1
Structure:
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