Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50421307
Substrate
n/a
Meas. Tech.
ChEMBL_840111 (CHEMBL2090814)
Kd
480000±n/a nM
Citation
 Liu, L; Li, C; Cochran, S; Feder, D; Guddat, LW; Ferro, V A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. Bioorg Med Chem Lett 22:6190-4 (2012) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM50421307
Synonyms:
CHEMBL2087901
Type:
Small organic molecule
Emp. Form.:
C18H23N2O16S3
Mol. Mass.:
619.576
SMILES:
CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: