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Target
Delta-aminolevulinic acid dehydratase
Ligand
BDBM50437871
Substrate
n/a
Meas. Tech.
ChEMBL_973999 (CHEMBL2410324)
Ki
200000000±n/a nM
Citation
 Suzuki, C; Kato, K; Tsuji, AB; Kikuchi, T; Zhang, MR; Arano, Y; Saga, T Synthesis and in vitro cellular uptake of 11C-labeled 5-aminolevulinic acid derivative to estimate the induced cellular accumulation of protoporphyrin IX. Bioorg Med Chem Lett 23:4567-70 (2013) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase
Synonyms:
ALAD | ALADH | HEM2_HUMAN | Porphobilinogen synthase
Type:
PROTEIN
Mol. Mass.:
36296.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1365623
Residue:
330
Sequence:
MQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYTPQLLQWLKEE
  
Inhibitor
Name:
BDBM50437871
Synonyms:
CHEMBL2407927
Type:
Small organic molecule
Emp. Form.:
C6H11NO3
Mol. Mass.:
145.1564
SMILES:
CC(N)C(=O)CCC(O)=O
Structure:
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