Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50073588
Substrate
n/a
Meas. Tech.
ChEMBL_1467413 (CHEMBL3411697)
Ki
0.870000±n/a nM
Citation
 Banister, SD; Beinat, C; Wilkinson, SM; Shen, B; Bartoli, C; Selleri, S; Da Pozzo, E; Martini, C; Chin, FT; Kassiou, M Ether analogues of DPA-714 with subnanomolar affinity for the translocator protein (TSPO). Eur J Med Chem 93:392-400 (2015) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50073588
Synonyms:
CHEMBL3408974
Type:
Small organic molecule
Emp. Form.:
C19H25FN2O
Mol. Mass.:
316.413
SMILES:
CCN(CC)C(=O)[C@H]1CCCc2c1c1ccccc1n2CCF |r|
Structure:
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