Compile Data Set for Download or QSAR
Report error Found 964 Enz. Inhib. hit(s) with all data for entry = 13111
TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759620(US20250236608, Example 212)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759861(US20250236608, Example 464)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759456((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759787((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759614(US20250236608, Example 206)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759662((1S,5S)—N-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759670(US20250236608, Example 264)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759547(US20250236608, Example 136)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759620(US20250236608, Example 212)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759724(US20250236608, Example 318)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759788((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759842(US20250236608, Example 439)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759779((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759847(US20250236608, Example 444)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759846(US20250236608, Example 443)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759703(US20250236608, Example 297)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759791((1S,5S)—N-(4-(1-ethyl-3-phenyl-1H-pyrazol-4-yl)-7-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759456((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759765(US20250236608, Example 362)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759700(US20250236608, Example 294)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759561(US20250236608, Example 153)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759544((S)-7-methoxy-4-(3-phenyl-1H-pyrazol-4-yl)-6-(tetr...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759424(US20250236608, Example 20)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759847(US20250236608, Example 444)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759670(US20250236608, Example 264)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759455((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759621(US20250236608, Example 213)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759890(US20250236608, Example 496)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759668((1R,5R)—N-(4-(1-ethyl-3-(2-fluorophenyl)-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759514((S)-1-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazol-4-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759849((R)-1-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759610(US20250236608, Example 202)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759528((S)-1-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759821(US20250236608, Example 418)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759785((1S,5S)—N-(4-(3-(4-fluorophenyl)-1-methyl-1H-pyraz...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759518((S)-1-(7-ethoxy-4-(1-ethyl-3-phenyl-1H-pyrazol-4-y...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759726(US20250236608, Example 320)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759565(US20250236608, Example 157)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759834((1R,5R)—N-(7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759618(US20250236608, Example 210)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759812((1S,5S)—N-(4-(1-(cyclopropylmethyl)-3-phenyl-1H-py...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759655(US20250236608, Example 247)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759783((1S,5S)—N-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759844(US20250236608, Example 441)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759782((1S,5S)—N-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759781((1S,5S)—N-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759842(US20250236608, Example 439)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759881(US20250236608, Example 486)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759784((1S,5S)—N-(4-(3-(4-fluorophenyl)-1-methyl-1H-pyraz...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759852(US20250236608, Example 450)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

Displayed 1 to 50 (of 964 total ) | Next | Last >>
Jump to: