BDBM103869 US9695165, 52
SMILES CCn1c2cc(ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O)-c1ccc2OC(C)(C)CN(C(=O)C=C)c2c1
InChI Key InChIKey=YBNXZJUSCOLKML-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 103869
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 55nMAssay Description:MDA-MB453 cells were plated in 96-well cell culture plates at a density of 1x105 cells. Cells were allowed to attach, and growth media was replaced w...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair