BDBM50004897 (APV)2-Amino-5-phosphono-pentanoic acid::(R)-2-Amino-5-phosphono-pentanoic acid::(R)-2-amino-5-phosphonopentanoicacid::2-Amino-5-phosphono-pentanoic acid::2-Amino-5-phosphono-pentanoic acid anion::2-Amino-5-phosphono-pentanoic acid(D-AP5)::2-Amino-5-phosphono-pentanoic acid(R-AP5)::2-Amino-5-phosphono-pentanoic acid(S-AP5)::CHEMBL28862::DL-2-amino-5-phosphono valericacid::DL-2-amino-5-phosphonovaleric acid

SMILES C(C[C@H](C(=O)O)N)CP(=O)(O)O

InChI Key InChIKey=VOROEQBFPPIACJ-UHFFFAOYSA-N

Data  5 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004897   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  280nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  460nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor 1(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards AMPA receptor using [3H]AMPA as radioligand; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards Ionotropic glutamate receptor kainate using [3H]-kainic acid as radioligand; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed