BDBM50171897 (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid::(S)-2-(4-Chloro-phenoxy)-3-phenyl-propionic acid::(S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid::CHEMBL364748

SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1

InChI Key InChIKey=CPBLTMSKPQDJPW-AWEZNQCLSA-N

Data  9 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50171897   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  1.30nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  7.94E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human HepG2 cells cotransfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  3.89E+3nMAssay Description:Agonist activity at GAL4-fused PPARalpha (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  9.60E+3nMAssay Description:Agonist activity at GAL4-tagged human PPARgamma ligand binding domain expressed in HepG2 cells assessed as transactivation after 20 hrs by beta-galac...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain expressed in HepG2 cells assessed as transactivation after 20 hrs by beta-galac...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  2.69E+3nMAssay Description:Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClO3/c16-12-6-8-13(9-7-12)19-14(15(17)18)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)/t14-/m0/s1
Affinity DataEC50:  1.45E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human HepG2 cells cotransfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair