BDBM50248106 CHEMBL461101::ELTROMBOPAG::Eltrombopag olamine

SMILES: Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1cccc(-c2cccc(c2)C(O)=O)c1O

InChI Key: InChIKey=SVOQIEJWJCQGDQ-UHFFFAOYSA-N

Data: 4 KI  12 IC50  1 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50248106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily D member 3 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Thrombopoietin receptor (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
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N6-adenosine-methyltransferase catalytic subunit (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 2B1 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		8.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		2.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50248106 (CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine) Show SMILES Show InChI	GoogleScholar	UniChem		1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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