Affinity DataKi: 0.117nM ΔG°: -13.5kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.204nM ΔG°: -13.2kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.241nM ΔG°: -13.1kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.243nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.243nM ΔG°: -13.1kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.299nM ΔG°: -13.0kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.323nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.359nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.377nM ΔG°: -12.8kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.377nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.404nM ΔG°: -12.8kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.444nM ΔG°: -12.8kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.658nM ΔG°: -12.5kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.822nM ΔG°: -12.4kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.842nM ΔG°: -12.4kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 0.842nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as inhibition of phosphorylation of (GFP)-4-EBP1 protein after 30 mins by flu...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant mTOR (1360-2549) expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 after 30 mins by L...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
Affinity DataKi: 1.03nM ΔG°: -12.3kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
Affinity DataKi: 1.06nM ΔG°: -12.2kcal/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair