Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50038054
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181139((S)-2-amino-2-cyclopropyl-1-((S)-4-(2,5-difluoroph...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181138((S)-2-amino-1-((S)-4-(2,5-difluorophenyl)-2-(3-hyd...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181137((S)-1-((S)-4-(2,5-difluorophenyl)-2-(3-hydroxyphen...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24060((2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluoro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181142((S)-4-(2,5-difluorophenyl)-N-(2-hydroxyethyl)-2-(3...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24057(3-amino-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24062(2-hydroxyethyl N-[(2S)-1-[(2S)-4-(2,5-difluorophen...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24063((2S)-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50:  12nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24056((2S)-N-(3-aminopropyl)-4-(2,5-difluorophenyl)-N-me...)
Affinity DataIC50:  16nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198312((S)-1-(3-(2,5-difluorophenyl)-5-phenyl-4,5-dihydro...)
Affinity DataIC50:  26nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24055((2S)-4-(2,5-difluorophenyl)-N-(1-acetylpiperidin-4...)
Affinity DataIC50:  50nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24053(3-(2,5-difluorophenyl)-N,N-dimethyl-5-phenyl-4,5-d...)
Affinity DataIC50:  84nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198314((3aS,10R)-2-(5-amino-pentyl)-10-(3-hydroxy-phenyl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24127((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...)
Affinity DataIC50:  104nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164856(1-(3-(2,5-difluorophenyl)-5-phenyl-4,5-dihydropyra...)
Affinity DataIC50:  250nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198306(CHEMBL254192 | N-(3-aminopropyl)-N-((3-benzyl-7-ch...)
Affinity DataIC50:  280nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24127((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...)
Affinity DataIC50:  306nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24066(1-[(5S)-3-(2-chlorophenyl)-5-(3-hydroxyphenyl)-4,5...)
Affinity DataIC50:  450nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24135(7-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)
Affinity DataIC50:  808nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164864(3-(2,5-Difluoro-phenyl)-1-methanesulfonyl-5-phenyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164861(1-(3-(2,5-difluorophenyl)-5-(thiophen-2-yl)-4,5-di...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24110(2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24067(3,5-diaryl-4,5-dihydropyrazole, 8a | 3-(2,5-difluo...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164869(1-(3-(2-chlorophenyl)-5-phenyl-4,5-dihydropyrazol-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164867(1-(3-(2-fluorophenyl)-5-phenyl-4,5-dihydropyrazol-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198310(CHEMBL252140 | ethanesulfonate8-[3-(2-chloro-pheno...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198304(CHEMBL559207 | N-ethyl-2-(4-(3-(2-(trifluoromethyl...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24105(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198308((R)-2-methyl-4-phenyl-1,2,3,4,8,9-hexahydrofuro[2,...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164866(1-(3-(3-chlorophenyl)-5-phenyl-4,5-dihydropyrazol-...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198303((1S,2S,5S,9R,10R,11R,14S)-7-(2-hydroxypropan-2-yl)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198305(1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24107(2-ethyl-7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydrois...)
Affinity DataIC50:  2.52E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198313(2,6-dichloro-4-[2-(2-chloro-3-hydroxyphenyl)-1,2-b...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198307(2-(2-(8-hydroxyquinolin-2-yl)disulfanyl)quinolin-8...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed