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Target
Type-1 angiotensin II receptor
Ligand
BDBM50282288
Substrate
n/a
Meas. Tech.
ChEMBL_36163 (CHEMBL646975)
IC50
4500±n/a nM
Citation
 Yanagisawa, H; Amemiya, Y; Kanazaki, T; Fujimoto, K; Shimoji, Y; Fujimoto, Y; Sada, T; Mizuno, M; Koike, H Angiotensin II receptor antagonists: imidazoles and pyrroles bearing hydroxymethyl and carboxy substituents Bioorg Med Chem Lett 4:177-182 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor
Type:
PROTEIN
Mol. Mass.:
41107.81
Organism:
Bos taurus
Description:
ChEMBL_36779
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
  
Inhibitor
Name:
BDBM50282288
Synonyms:
1-(2'-Carboxy-biphenyl-4-ylmethyl)-3-methoxymethyl-5-propyl-1H-pyrrole-2-carboxylic acid | CHEMBL50592
Type:
Small organic molecule
Emp. Form.:
C24H25NO5
Mol. Mass.:
407.459
SMILES:
CCCc1cc(COC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Structure:
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