BDBM50277584 CHEMBL482968::N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine

SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(C=Cc2ccccc2)n1

InChI Key InChIKey=BLQYVHBZHAISJM-UHFFFAOYSA-N

Data  33 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277584   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CSF-stimulated CSF1R phosphorylation in human MV4-11 cells by immunoblotting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human His-tagged FMS expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed