BDBM50277584 CHEMBL482968::N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine

SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(C=Cc2ccccc2)n1

InChI Key InChIKey=BLQYVHBZHAISJM-UHFFFAOYSA-N

Data  33 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277584   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed