BDBM103838 MK-5172
SMILES COc1ccc2nc3CCCCC[C@@H]4C[C@H]4OC(=O)N[C@H](C(=O)N4CC(C[C@H]4C(=O)N[C@@]4(C[C@H]4C=C)C(=O)NS(=O)(=O)C4CC4)Oc3nc2c1)C(C)(C)C
InChI Key InChIKey=OBMNJSNZOWALQB-PDAHHYMFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 103838
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 0.0600nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.290nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair