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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM103838'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School

LigandPNGBDBM103838(MK-5172)
Affinity DataKi:  0.0600nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School

LigandPNGBDBM103838(MK-5172)
Affinity DataIC50:  0.290nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed