BDBM106583 CHEMBL2206381::US8586617, 25
SMILES COc1cccc(c1)N(Cc1cnc[nH]1)C(C)C
InChI Key InChIKey=DCFNZAPUZDWYSA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 106583
Affinity DataKi: 5nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nM ΔG°: -10.5kcal/moleT: 2°CAssay Description:Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at mouse TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 61nMAssay Description:Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair