BDBM106583 CHEMBL2206381::US8586617, 25

SMILES COc1cccc(c1)N(Cc1cnc[nH]1)C(C)C

InChI Key InChIKey=DCFNZAPUZDWYSA-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106583   

TargetTrace amine-associated receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106583(CHEMBL2206381 | US8586617, 25)
Affinity DataKi:  5nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106583(CHEMBL2206381 | US8586617, 25)
Affinity DataKi:  5.5nM ΔG°:  -10.5kcal/moleT: 2°CAssay Description:Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106583(CHEMBL2206381 | US8586617, 25)
Affinity DataEC50:  72nMAssay Description:Agonist activity at mouse TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106583(CHEMBL2206381 | US8586617, 25)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106583(CHEMBL2206381 | US8586617, 25)
Affinity DataEC50:  61nMAssay Description:Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed