BDBM14632 1-{5-chloro-4-[2-({2-[2-(dimethylamino)ethoxy]ethyl}(methyl)amino)ethoxy]-2-(pyrrolidin-1-yl)phenyl}-3-(5-cyanopyrazin-2-yl)urea::N-pyrazinylurea Analog 19c

SMILES CN(C)CCOCCN(C)CCOc1cc(N2CCCC2)c(NC(=O)Nc2cnc(cn2)C#N)cc1Cl

InChI Key InChIKey=JCENELKIRQPCKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14632   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM14632(1-{5-chloro-4-[2-({2-[2-(dimethylamino)ethoxy]ethy...)
Affinity DataIC50:  64nMAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed