BDBM17966 (6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phenyl)-6-[(naphthalen-2-yloxy)methyl]piperazin-2-one::CHEMBL371426::Ketopiperazine-based compound, 2
SMILES COc1ccccc1COCCCOc1ccc(cc1)N1[C@@H](COc2ccc3ccccc3c2)CNCC1=O
InChI Key InChIKey=YNZFVUGNLOWSTD-MUUNZHRXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 17966
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair