Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM17966'
TargetRenin(Homo sapiens (Human))
Pfizer

LigandPNGBDBM17966((6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50:  54nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

LigandPNGBDBM17966((6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

LigandPNGBDBM17966((6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50:  54nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed