BDBM18133 2-aminoacetic acid::CHEMBL773::Glycine::[14C]Glycine

SMILES NCC(O)=O

InChI Key InChIKey=DHMQDGOQFOQNFH-UHFFFAOYSA-N

Data  4 KI  6 IC50  5 EC50

PDB links: 70 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18133   

TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataEC50:  9.55E+4nMAssay Description:Antagonist activity at human glycine alpha-1 receptor in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataEC50:  990nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair