BDBM18133 2-aminoacetic acid::CHEMBL773::Glycine::[14C]Glycine

SMILES NCC(O)=O

InChI Key InChIKey=DHMQDGOQFOQNFH-UHFFFAOYSA-N

Data  4 KI  6 IC50  5 EC50

PDB links: 70 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 18133   

TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50:  2.24E+6nMAssay Description:Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50:  1.35E+6nMAssay Description:Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity of the compound to inhibit [3H]-glycine binding to NMDA receptorMore data for this Ligand-Target Pair
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human LAT1 expressed in HEK293-T-Rex cells assessed as inhibition of [3H]-gabapentin uptake by scintillation counting cis-inhibition as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of GlyT1 (unknown origin) assessed as inhibition of [14C]glycine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank