BDBM21283 3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpiperidin-2-yl)methyl]-1H-indole::AM1241

SMILES CN1CCCCC1Cn1cc(C(=O)c2cc(ccc2I)[N+]([O-])=O)c2ccccc12

InChI Key InChIKey=ZUHIXXCLLBMBDW-UHFFFAOYSA-N

Data  16 KI  2 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21283   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  11.5nM EC50: >1.00E+4nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  1.27E+3nM ΔG°:  -8.17kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed