BDBM21353 2-{1-[(3,4-dimethoxybenzene)sulfonyl]-1H-indol-3-yl}ethan-1-amine::Substituted phenylsulfonyltryptamine, 11l

SMILES COc1ccc(cc1OC)S(=O)(=O)n1cc(CCN)c2ccccc12

InChI Key InChIKey=NXNLNVGGTUZXJZ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21353   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM21353(2-{1-[(3,4-dimethoxybenzene)sulfonyl]-1H-indol-3-y...)
Affinity DataKi:  7nM ΔG°:  -11.0kcal/mole EC50:  17.5nMpH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed