BDBM22319 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid::Arachidonic acid::Arachidonic acid (AA)::CHEMBL15594::[1-14C]Arachidonic acid
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
InChI Key InChIKey=YZXBAPSDXZZRGB-DOFZRALJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 22319
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
University Of Parma
Curated by ChEMBL
University Of Parma
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Binding affinity against Adipocyte lipid binding proteinMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity towards Nurr1 ligand binding domain (unknown origin) measured by tryptophan fluorescence spectroscopyMore data for this Ligand-Target Pair
TargetFatty acid-binding protein 5-ANS(Mus musculus (Mouse))
Case Western Reserve University School of Medicine
Case Western Reserve University School of Medicine
Affinity DataKd: 42.1nMAssay Description:The method entails two steps [Lin et al., Biochemistry, 38:185-190]. In the first step, the Kd for association of FABP5 with the fluorescent lipid pr...More data for this Ligand-Target Pair
Affinity DataKd: 8.07E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 22319
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -11.2kcal/mole −TΔS°: 3.33kcal/mole ΔH°: -14.2kcal/mole logk: 7.69E+7
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -12.3kcal/mole −TΔS°: 2.30kcal/mole ΔH°: -11.0kcal/mole logk: 4.35E+8
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2 I332A)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -8.18kcal/mole −TΔS°: 6.44kcal/mole ΔH°: -14.5kcal/mole logk: 5.88E+5
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2 V309D)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -7.69kcal/mole −TΔS°: 1.93kcal/mole ΔH°: -9.31kcal/mole logk: 2.63E+5
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C