BDBM22319 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid::Arachidonic acid::Arachidonic acid (AA)::CHEMBL15594::[1-14C]Arachidonic acid
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
InChI Key InChIKey=YZXBAPSDXZZRGB-DOFZRALJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 22319
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.59E+3nM ΔG°: -7.74kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nM ΔG°: -7.35kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Affinity DataKi: 9.37E+3nM ΔG°: -6.97kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 22319
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -11.2kcal/mole −TΔS°: 3.33kcal/mole ΔH°: -14.2kcal/mole logk: 7.69E+7
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -12.3kcal/mole −TΔS°: 2.30kcal/mole ΔH°: -11.0kcal/mole logk: 4.35E+8
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2 I332A)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -8.18kcal/mole −TΔS°: 6.44kcal/mole ΔH°: -14.5kcal/mole logk: 5.88E+5
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C
CellMannoprotein ligand-binding domain 2 (Mp1p-LBD2 V309D)(Talaromyces marneffei)
The University of Hong Kong
The University of Hong Kong
ITC DataΔG°: -7.69kcal/mole −TΔS°: 1.93kcal/mole ΔH°: -9.31kcal/mole logk: 2.63E+5
pH: 8.0 T: 37.00°C
pH: 8.0 T: 37.00°C