BDBM22372 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol::4-[(2S,3R)-3-[(3,4-dihydroxyphenyl)methyl]-2-methylbutyl]benzene-1,2-diol::CHEMBL313972::Masoprocol::NDGA::Nordihydroguaiaretic Acid

SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1

InChI Key InChIKey=HCZKYJDFEPMADG-TXEJJXNPSA-N

Data  36 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22372   

TargetProstaglandin G/H synthase 1/2(Bos taurus)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM22372(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM22372(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)
Affinity DataIC50:  150nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed