BDBM22417 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine::CHEMBL295467::LY 135252::LY 94939::LY135252::LY139602::Nisoxetine::Nisoxetine Inhibitor::US9944618, Compound ID No. 177::[3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine::[3H]Nisoxetine

SMILES CNCCC(Oc1ccccc1OC)c1ccccc1

InChI Key InChIKey=ITJNARMNRKSWTA-UHFFFAOYSA-N

Data  41 KI  22 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22417   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataKi:  6nM ΔG°:  -11.7kcal/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed