BDBM22417 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine::CHEMBL295467::LY 135252::LY 94939::LY135252::LY139602::Nisoxetine::Nisoxetine Inhibitor::US9944618, Compound ID No. 177::[3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine::[3H]Nisoxetine

SMILES CNCCC(Oc1ccccc1OC)c1ccccc1

InChI Key InChIKey=ITJNARMNRKSWTA-UHFFFAOYSA-N

Data  41 KI  22 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22417   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed