BDBM225266 2-((5-Chloro-2-hydroxyphenyl)(methyl)amino)-N-(3-(morpholinosulfonyl)phe-nyl)acetamide (7b)

SMILES CN(CC(=O)Nc1cccc(c1)S(=O)(=O)N1CCOCC1)c1cc(Cl)ccc1O

InChI Key InChIKey=YJOFVIHYKQOFIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 225266   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM225266(2-((5-Chloro-2-hydroxyphenyl)(methyl)amino)-N-(3-(...)
Affinity DataIC50:  9.50E+3nMpH: 7.5 T: 2°CAssay Description:The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM225266(2-((5-Chloro-2-hydroxyphenyl)(methyl)amino)-N-(3-(...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human LSD1 (158 to end residues) expressed in Escherichia coli preincubated for 15 mins followed by H3K4me2 peptide addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM225266(2-((5-Chloro-2-hydroxyphenyl)(methyl)amino)-N-(3-(...)
Affinity DataIC50:  6.57E+4nMAssay Description:The MAO-A and MAO-B is purchased from Active Motif (Cat#31502, Cat#31503). Biochemical Kit is purchased from Promega (MAO-Glo Assay, V1402). The inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM225266(2-((5-Chloro-2-hydroxyphenyl)(methyl)amino)-N-(3-(...)
Affinity DataIC50:  1.87E+5nMAssay Description:The MAO-A and MAO-B is purchased from Active Motif (Cat#31502, Cat#31503). Biochemical Kit is purchased from Promega (MAO-Glo Assay, V1402). The inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed