BDBM22881 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine::Amthamine::CHEMBL554964

SMILES Cc1nc(N)sc1CCN

InChI Key InChIKey=LHVRFUVVRXGZPV-UHFFFAOYSA-N

Data  3 KI  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22881   

TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22881(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22881(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22881(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Affinity DataEC50:  1.58E+4nMAssay Description:Agonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed