BDBM22881 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine::Amthamine::CHEMBL554964

SMILES Cc1nc(N)sc1CCN

InChI Key InChIKey=LHVRFUVVRXGZPV-UHFFFAOYSA-N

Data  3 KI  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22881   

TargetHistamine H2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22881(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Affinity DataKd:  1.15E+4nMAssay Description:Affinity to the Histamine H2 receptor was determined expressed in CHO cell using [125I]iodoaminopotentidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22881(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Affinity DataKd:  5.01E+3nMAssay Description:Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed