BDBM23518 2-[3-(naphthalen-2-yl)propanamido]benzoic acid::Biaryl Anthranilide Analogue, 1b::CHEMBL235740

SMILES OC(=O)c1ccccc1NC(=O)CCc1ccc2ccccc2c1

InChI Key InChIKey=TUCHRHOVXUFQLY-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23518   

TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataIC50:  140nM EC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed