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Found 4 Enz. Inhib. hit(s) with Target = 'Hydroxycarboxylic acid receptor 2' and Ligand = 'BDBM23518'
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataIC50:  140nM EC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | B...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed