BDBM241940 US9422333, I-1

SMILES CC(C)(C)NC(=O)N[C@@H](CNC(=O)C=C)C(=O)N1CC2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C

InChI Key InChIKey=SWJQTCTXGIEKDV-ZFHYAEIBSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 241940   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  290nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  312nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,R155K](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  928nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,C159S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  1.09E+3nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,C159S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: >3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,A156S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: >3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  2.55E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,R155K](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: >3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  1.33E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent