BDBM249400 US10537571, Compound 113::US10912774, Compound 113::US9434697, 113::US9730931, Compound 113

SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(CN(C)C)cc3NC(=O)C=C)ncn2)c1Cl

InChI Key InChIKey=KEVACVIEXZWWQA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249400   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM249400(US10537571, Compound 113 | US10912774, Compound 11...)
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM249400(US10537571, Compound 113 | US10912774, Compound 11...)
Affinity DataIC50:  621nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent