BDBM249400 US10537571, Compound 113::US10912774, Compound 113::US9434697, 113::US9730931, Compound 113

SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(CN(C)C)cc3NC(=O)C=C)ncn2)c1Cl

InChI Key InChIKey=KEVACVIEXZWWQA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249400   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM249400(US10537571, Compound 113 | US10912774, Compound 11...)
Affinity DataIC50:  621nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen™) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM249400(US10537571, Compound 113 | US10912774, Compound 11...)
Affinity DataIC50: <1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen™) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent