BDBM25124 (2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chlorophenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 3

SMILES Nc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc(\C=C\C(O)=O)cc1Cl

InChI Key InChIKey=MDZHCLVOVABFGD-QHHAFSJGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25124   

TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25124((2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chl...)
Affinity DataIC50:  1.83E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed