BDBM25290 CHEMBL56073::bisphosphonate, 39::{1-hydroxy-3-[methyl(4-phenylbutyl)amino]-1-phosphonopropyl}phosphonic acid
SMILES CN(CCCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
InChI Key InChIKey=VFLFYDXGZMGUAF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 25290
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Illinois At Urbana - Champaign
Curated by ChEMBL
University Of Illinois At Urbana - Champaign
Curated by ChEMBL
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Negative logarithm of inhibitory concentration against bone resorptionMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Escherichia coli K-12)
University Of Illinois At Urbana - Champaign
Curated by ChEMBL
University Of Illinois At Urbana - Champaign
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli FPPSMore data for this Ligand-Target Pair
Affinity DataIC50: 4.17E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
TargetPolyprenyl synthetase family protein(Plasmodium falciparum (isolate 3D7))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair