BDBM27339 9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophenyl)-9H-purin-6-amine::Purine antagonist, 3c

SMILES Clc1ccc(cc1)-n1c(nc2c(NC3CCCCC3)ncnc12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=ICLCHVCUUGMJML-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27339   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27339(9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophe...)
Affinity DataKi:  7.10nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27339(9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophe...)
Affinity DataKi:  12nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed