BDBM322472 (R)-N-(2,2-dimethylquinuclidin-3-yl)imidazo[1,2-a]pyrazine-6-carboxamide::US10183938, Compound (R)-225

SMILES CC1(C)[C@H](NC(=O)c2cn3ccnc3cn2)C2CCN1CC2

InChI Key InChIKey=RRMAYDAZJQJECJ-CQSZACIVSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 322472   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322472((R)-N-(2,2-dimethylquinuclidin-3-yl)imidazo[1,2-a]...)
Affinity DataKi: >3.00E+4nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent