BDBM343202 (M)-4-(2-chloro-3''-fluoro-5-methoxy-4-biphenylyl)-3-ethyl-N-3-isoxazolyl-7-cinnolinesulfonamide::US9776995, Example 443::US9776995, Example 444

SMILES CCc1nnc2cc(ccc2c1-c1cc(Cl)c(cc1OC)-c1cccc(F)c1)S(=O)(=O)Nc1ccon1

InChI Key InChIKey=GMBVTSQIXFKSRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343202   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343202((M)-4-(2-chloro-3''-fluoro-5-methoxy-4-biphenylyl)...)
Affinity DataIC50:  1.16E+3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343202((M)-4-(2-chloro-3''-fluoro-5-methoxy-4-biphenylyl)...)
Affinity DataIC50:  87nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent