BDBM356878 US10214492, Example 229::US11292767, Example 229

SMILES CCn1ncc2ccc(cc12)-c1cc(COC(C)(C)C(O)=O)nn1-c1ccccc1N1CCCC1

InChI Key InChIKey=DNRJFKUHHRXVPH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 356878   

TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356878(US10214492, Example 229 | US11292767, Example 229)
Affinity DataIC50:  1.90nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356878(US10214492, Example 229 | US11292767, Example 229)
Affinity DataIC50:  4.20E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356878(US10214492, Example 229 | US11292767, Example 229)
Affinity DataIC50:  1.90nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356878(US10214492, Example 229 | US11292767, Example 229)
Affinity DataIC50:  4.20E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent