BDBM3583 5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazoline::Anilinopyrimidine deriv. 7b::N-(3-bromophenyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 21::Pyrroloquinazoline deriv. 3a

SMILES Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1

InChI Key InChIKey=BBFWQWIFLDQYQQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3583   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3583(5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazol...)
Affinity DataIC50:  0.440nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3583(5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazol...)
Affinity DataIC50:  21.9nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3583(5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazol...)
Affinity DataIC50:  0.390nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3583(5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazol...)
Affinity DataIC50:  0.440nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed