BDBM37953 US10093631, Compound Lesinurad::US10336710, Lesinurad::US10752613, Compound Lesinurad::US11020397, Compound Lesinurad::US11149013, Compound lesinurad::US11161835, Compound Lesinurad
SMILES OC(=O)CSc1nnc(Br)n1-c1ccc(C2CC2)c2ccccc12
InChI Key InChIKey=JHWDCJBLPGLDMI-UHFFFAOYSA-N
Data 45 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 37953
Affinity DataIC50: 1.86E+4nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+4nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair