BDBM50024831 1,2,3,4-Tetrahydro-isoquinoline-6,7-diol::CHEMBL11862

SMILES Oc1cc2CCNCc2cc1O

InChI Key InChIKey=MBFUSGLXKQWVDW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50024831   

LigandPNGBDBM50024831(1,2,3,4-Tetrahydro-isoquinoline-6,7-diol | CHEMBL1...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024831(1,2,3,4-Tetrahydro-isoquinoline-6,7-diol | CHEMBL1...)
Affinity DataKi:  4.47E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024831(1,2,3,4-Tetrahydro-isoquinoline-6,7-diol | CHEMBL1...)
Affinity DataKi:  5.70E+3nMAssay Description:In vitro inhibition of bovine phenylethylamine N-methyl-transferase (PNMT) using radiochemical assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed